Gout: will the “King of Diseases” be the first rheumatic disease to be cured?

Gout: will the “King of Diseases” be the first rheumatic disease to be cured?

Gout is the most common inflammatory arthritis in adults in the Western world. Characterized by hyperuricemia and the effects of acute and chronic inflammation in joints and bursa, gout leads to an agonizing, chronically painful arthritis. Arthritis can also be accompanied by urate nephropathy and subcutaneous urate deposits (tophi). Exciting new developments in the last decade have brought bac...

A case of acute rheumatic fever with new criteria, a disease that needs to be considered

Introduction: Acute rheumatic fever is an autoimmune disease that mainly affects the large joints. Early treatment of a throat infection following group A streptococcus prevents of acute rheumatic fever. Given the low prevalence of the disease, especially in a situation where there is excessive use of antibiotics in Iran, this study intends to report a patient with Acute rheumatic fever with mi...

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Leaders Prion diseases: what will be next?

In recent history there is probably no group of disease that has caused more surprises or shocks than the group of transmissible spongiform encephalopathies, or prion diseases as they have become known. Grouped together on the basis of their neuropathology, showing vacuolation of the neuropil or neurones, or both (spongiform change) (fig 1), they present a variable clinical picture; nevertheles...

The sirolimus coated stent: will the Achilles heel of interventional cardiology finally be cured?

coronary artery disease. Am J Cardiol 1973; 32: 257–63. [13] Legrand V, Hodgson JM, Bates ER et al. Abnormal coronary flow reserve and abnormal radionuclide exercise test results in patients with normal coronary angiograms. J Am Coll Cardiol 1985; 6: 1245–53. [14] Levy RD, Cunningham D, Shapiro LM, Wright C, Mockus L, Fox KM. Diurnal variation in left ventricular function: a study of patients w...